About Stromal cell-derived factor 2-like protein 1
Stromal cell-derived factor 2-like protein 1 (SDF2L1) is a protein
from Homo sapiens identified by UniProt accession
Q9HCN8, 221 residues long.
MolForge cross-references it against 0 known binders and
41 disease associations.
Target properties
| Protein name | Stromal cell-derived factor 2-like protein 1 |
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| UniProt accession | Q9HCN8 |
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| Gene | SDF2L1 |
|---|
| Organism | Homo sapiens |
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| Length | 221 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (41)
Diseases linked to this target (Open Targets).
- rheumatoid arthritis · score 0.25
- reticulocyte count · score 0.09
- arterial stiffness measurement · score 0.07
- eosinophil percentage of leukocytes · score 0.03
- vital capacity · score 0.03
- mucous membrane pemphigoid · score 0.03
- pulse pressure measurement · score 0.02
- Insulin resistance · score 0.02
- diabetes mellitus · score 0.02
- eosinophil count · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9HCN8-F1 | alphafold | PREDICTED | 88.39 | — |
Amino-acid sequence (221 residues)
MWSAGRGGAA WPVLLGLLLA LLVPGGGAAK TGAELVTCGS VLKLLNTHHR VRLHSHDIKY GSGSGQQSVT GVEASDDANS YWRIRGGSEG GCPRGSPVRC GQAVRLTHVL TGKNLHTHHF PSPLSNNQEV SAFGEDGEGD DLDLWTVRCS GQHWEREAAV RFQHVGTSVF LSVTGEQYGS PIRGQHEVHG MPSANTHNTW KAMEGIFIKP SVEPSAGHDE L
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