About Pro-FMRFamide-related neuropeptide VF
Pro-FMRFamide-related neuropeptide VF (NPVF) is a protein
from Homo sapiens identified by UniProt accession
Q9HCQ7, 196 residues long.
MolForge cross-references it against 0 known binders and
23 disease associations.
Target properties
| Protein name | Pro-FMRFamide-related neuropeptide VF |
|---|
| UniProt accession | Q9HCQ7 |
|---|
| Gene | NPVF |
|---|
| Organism | Homo sapiens |
|---|
| Length | 196 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (23)
Diseases linked to this target (Open Targets).
- body height · score 0.35
- BMI-adjusted waist circumference · score 0.34
- body fat percentage · score 0.33
- hemoglobin measurement · score 0.29
- hematocrit · score 0.27
- heel bone mineral density · score 0.25
- bone quantitative ultrasound measurement · score 0.23
- erythrocyte count · score 0.19
- lobe attachment · score 0.17
- bone density · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9HCQ7-F1 | alphafold | PREDICTED | 58.48 | — |
Amino-acid sequence (196 residues)
MEIISSKLFI LLTLATSSLL TSNIFCADEL VMSNLHSKEN YDKYSEPRGY PKGERSLNFE ELKDWGPKNV IKMSTPAVNK MPHSFANLPL RFGRNVQEER SAGATANLPL RSGRNMEVSL VRRVPNLPQR FGRTTTAKSV CRMLSDLCQG SMHSPCANDL FYSMTCQHQE IQNPDQKQSR RLLFKKIDDA ELKQEK
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