Protein S100-A14 (S100A14)

About Protein S100-A14

Protein S100-A14 (S100A14) is a protein from Homo sapiens identified by UniProt accession Q9HCY8, 104 residues long. MolForge cross-references it against 0 known binders and 44 disease associations.

Target properties

Protein name	Protein S100-A14
UniProt accession	Q9HCY8
Gene	S100A14
Organism	Homo sapiens
Length	104 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (44)

Diseases linked to this target (Open Targets).

platelet crit · score 0.14
platelet count · score 0.12
Familial exudative vitreoretinopathy · score 0.05
non-small cell lung carcinoma · score 0.05
X-linked retinal dysplasia · score 0.04
severe early-childhood-onset retinal dystrophy · score 0.04
Familial drusen · score 0.04
neoplasm · score 0.04
blood protein measurement · score 0.04
X-linked retinoschisis · score 0.04

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9HCY8-F1	alphafold	PREDICTED	76.59	—

Amino-acid sequence (104 residues)

MGQCRSANAE DAQEFSDVER AIETLIKNFH QYSVEGGKET LTPSELRDLV TQQLPHLMPS NCGLEEKIAN LGSCNDSKLE FRSFWELIGE AAKSVKLERP VRGH

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards