Large ribosomal subunit protein uL29m (MRPL47)

Homo sapiens — UniProt Q9HD33

Gene: MRPL47Homo sapiensSwissProt reviewed

About Large ribosomal subunit protein uL29m

Large ribosomal subunit protein uL29m (MRPL47) is a protein from Homo sapiens identified by UniProt accession Q9HD33, 250 residues long. MolForge cross-references it against 0 known binders and 12 disease associations.

Target properties

Protein nameLarge ribosomal subunit protein uL29m
UniProt accessionQ9HD33
GeneMRPL47
OrganismHomo sapiens
Length250 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

Disease associations (12)

Diseases linked to this target (Open Targets).

  • Abnormal sperm morphology · score 0.02
  • breast carcinoma · score 0.01
  • ovarian carcinoma · score 0.01
  • Alzheimer disease · score 0.01
  • Vitiligo · score 0.01
  • acute lymphoblastic leukemia · score 0.00
  • cancer · score 0.00
  • hepatocellular carcinoma · score 0.00
  • cervical squamous cell carcinoma · score 0.00
  • visceral Leishmaniasis · score 0.00

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9HD33-F1alphafoldPREDICTED82.72—

Amino-acid sequence (250 residues)

MAAAGLALLC RRVSSALKSS RSLITPQVPA CTGFFLSLLP KSTPNVTSFH QYRLLHTTLS RKGLEEFFDD PKNWGQEKVK SGAAWTCQQL RNKSNEDLHK LWYVLLKERN MLLTLEQEAK RQRLPMPSPE RLDKVVDSMD ALDKVVQERE DALRLLQTGQ ERARPGAWRR DIFGRIIWHK FKQWVIPWHL NKRYNRKRFF ALPYVDHFLR LEREKRARIK ARKENLERKK AKILLKKFPH LAEAQKSSLV

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Quick facts

UniProtQ9HD33
GeneMRPL47
OrganismHomo sapiens
Length250
Binders0
Diseases12
View on UniProt