About Large ribosomal subunit protein uL29m
Large ribosomal subunit protein uL29m (MRPL47) is a protein
from Homo sapiens identified by UniProt accession
Q9HD33, 250 residues long.
MolForge cross-references it against 0 known binders and
12 disease associations.
Target properties
| Protein name | Large ribosomal subunit protein uL29m |
| UniProt accession | Q9HD33 |
| Gene | MRPL47 |
| Organism | Homo sapiens |
| Length | 250 residues |
| Molecular weight | — |
| EC numbers | — |
| Target class | UNCLASSIFIED |
| Subcellular location | — |
| Keywords | — |
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
| Druggability score | — |
| Pocket score | — |
| Max clinical phase | — |
Disease associations (12)
Diseases linked to this target (Open Targets).
- Abnormal sperm morphology · score 0.02
- breast carcinoma · score 0.01
- ovarian carcinoma · score 0.01
- Alzheimer disease · score 0.01
- Vitiligo · score 0.01
- acute lymphoblastic leukemia · score 0.00
- cancer · score 0.00
- hepatocellular carcinoma · score 0.00
- cervical squamous cell carcinoma · score 0.00
- visceral Leishmaniasis · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
| AF-Q9HD33-F1 | alphafold | PREDICTED | 82.72 | — |
Amino-acid sequence (250 residues)
MAAAGLALLC RRVSSALKSS RSLITPQVPA CTGFFLSLLP KSTPNVTSFH QYRLLHTTLS RKGLEEFFDD PKNWGQEKVK SGAAWTCQQL RNKSNEDLHK LWYVLLKERN MLLTLEQEAK RQRLPMPSPE RLDKVVDSMD ALDKVVQERE DALRLLQTGQ ERARPGAWRR DIFGRIIWHK FKQWVIPWHL NKRYNRKRFF ALPYVDHFLR LEREKRARIK ARKENLERKK AKILLKKFPH LAEAQKSSLV
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