LYR motif-containing protein 4 (LYRM4)

About LYR motif-containing protein 4

LYR motif-containing protein 4 (LYRM4) is a protein from Homo sapiens identified by UniProt accession Q9HD34, 91 residues long. MolForge cross-references it against 0 known binders and 48 disease associations.

Target properties

Protein name	LYR motif-containing protein 4
UniProt accession	Q9HD34
Gene	LYRM4
Organism	Homo sapiens
Length	91 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (48)

Diseases linked to this target (Open Targets).

combined oxidative phosphorylation deficiency 19 · score 0.68
Red cell distribution width · score 0.41
diet measurement · score 0.21
body weight · score 0.13
breast milk measurement · score 0.08
metabolite measurement · score 0.08
PHF-tau measurement · score 0.04
neoplasm · score 0.03
systemic juvenile idiopathic arthritis · score 0.02
cancer · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9HD34-F1	alphafold	PREDICTED	93.15	—

Amino-acid sequence (91 residues)

MAASSRAQVL SLYRAMLRES KRFSAYNYRT YAVRRIRDAF RENKNVKDPV EIQTLVNKAK RDLGVIRRQV HIGQLYSTDK LIIENRDMPR T

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards