About Bcl-2-like protein 10
Bcl-2-like protein 10 (BCL2L10) is a protein
from Homo sapiens identified by UniProt accession
Q9HD36, 204 residues long.
MolForge cross-references it against 0 known binders and
63 disease associations.
Target properties
| Protein name | Bcl-2-like protein 10 |
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| UniProt accession | Q9HD36 |
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| Gene | BCL2L10 |
|---|
| Organism | Homo sapiens |
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| Length | 204 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (63)
Diseases linked to this target (Open Targets).
- small cell lung carcinoma · score 0.33
- follicular lymphoma · score 0.10
- hepatocellular carcinoma · score 0.10
- myelodysplastic syndrome · score 0.10
- myelofibrosis · score 0.09
- Hodgkins lymphoma · score 0.09
- melanoma · score 0.09
- acute myeloid leukemia · score 0.08
- Miyoshi myopathy · score 0.07
- chronic lymphocytic leukemia · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9HD36-F1 | alphafold | PREDICTED | 85.12 | — |
Amino-acid sequence (204 residues)
MVDQLRERTT MADPLRERTE LLLADYLGYC AREPGTPEPA PSTPEAAVLR SAAARLRQIH RSFFSAYLGY PGNRFELVAL MADSVLSDSP GPTWGRVVTL VTFAGTLLER GPLVTARWKK WGFQPRLKEQ EGDVARDCQR LVALLSSRLM GQHRAWLQAQ GGWDGFCHFF RTPFPLAFWR KQLVQAFLSC LLTTAFIYLW TRLL
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