About Charged multivesicular body protein 1a
Charged multivesicular body protein 1a (CHMP1A) is a protein
from Homo sapiens identified by UniProt accession
Q9HD42, 196 residues long.
MolForge cross-references it against 0 known binders and
113 disease associations.
Target properties
| Protein name | Charged multivesicular body protein 1a |
|---|
| UniProt accession | Q9HD42 |
|---|
| Gene | CHMP1A |
|---|
| Organism | Homo sapiens |
|---|
| Length | 196 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (113)
Diseases linked to this target (Open Targets).
- pontocerebellar hypoplasia type 8 · score 0.76
- viral disease · score 0.46
- pontocerebellar hypoplasia · score 0.44
- genetic disorder · score 0.41
- diastolic blood pressure · score 0.27
- Non-syndromic pontocerebellar hypoplasia · score 0.27
- autosomal recessive non-syndromic intellectual disability · score 0.27
- pontocerebellar hypoplasia type 1 · score 0.27
- hemoglobin measurement · score 0.22
- erythrocyte count · score 0.22
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9HD42-F1 | alphafold | PREDICTED | 77.91 | — |
Amino-acid sequence (196 residues)
MDDTLFQLKF TAKQLEKLAK KAEKDSKAEQ AKVKKALLQK NVECARVYAE NAIRKKNEGV NWLRMASRVD AVASKVQTAV TMKGVTKNMA QVTKALDKAL STMDLQKVSS VMDRFEQQVQ NLDVHTSVME DSMSSATTLT TPQEQVDSLI MQIAEENGLE VLDQLSQLPE GASAVGESSV RSQEDQLSRR LAALRN
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