X antigen family member 1 (XAGE1A)

About X antigen family member 1

X antigen family member 1 (XAGE1A) is a protein from Homo sapiens identified by UniProt accession Q9HD64, 81 residues long. MolForge cross-references it against 0 known binders and 49 disease associations.

Target properties

Protein name	X antigen family member 1
UniProt accession	Q9HD64
Gene	XAGE1A
Organism	Homo sapiens
Length	81 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (49)

Diseases linked to this target (Open Targets).

neoplasm · score 0.08
hepatocellular carcinoma · score 0.05
melanoma · score 0.05
non-small cell lung carcinoma · score 0.03
cancer · score 0.03
lung adenocarcinoma · score 0.03
adenocarcinoma · score 0.02
ovarian cancer · score 0.02
Ewing sarcoma · score 0.01
Acute Leukemia · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9HD64-F1	alphafold	PREDICTED	50.62	—

Amino-acid sequence (81 residues)

MESPKKKNQQ LKVGILHLGS RQKKIRIQLR SQCATWKVIC KSCISQTPGI NLDLGSGVKV KIIPKEEHCK MPEAGEEQPQ V

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards