Resistin (RETN)

About Resistin

Resistin (RETN) is a protein from Homo sapiens identified by UniProt accession Q9HD89, 108 residues long. MolForge cross-references it against 0 known binders and 581 disease associations.

Target properties

Protein name	Resistin
UniProt accession	Q9HD89
Gene	RETN
Organism	Homo sapiens
Length	108 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (581)

Diseases linked to this target (Open Targets).

resistin measurement · score 0.34
cerebrospinal fluid biomarker measurement · score 0.18
type 2 diabetes mellitus · score 0.13
Sepsis · score 0.11
insulin resistance · score 0.11
polycystic ovary syndrome · score 0.11
gestational diabetes · score 0.11
non-alcoholic fatty liver disease · score 0.10
breast cancer · score 0.10
mucocutaneous lymph node syndrome · score 0.10

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9HD89-F1	alphafold	PREDICTED	89.46	—

Amino-acid sequence (108 residues)

MKALCLLLLP VLGLLVSSKT LCSMEEAINE RIQEVAGSLI FRAISSIGLE CQSVTSRGDL ATCPRGFAVT GCTCGSACGS WDVRAETTCH CQCAGMDWTG ARCCRVQP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards