About Endogenous retrovirus group K member 5 Gag polyprotein
Endogenous retrovirus group K member 5 Gag polyprotein (ERVK-5) is a protein
from Homo sapiens identified by UniProt accession
Q9HDB9, 667 residues long.
MolForge cross-references it against 0 known binders and
0 disease associations.
Target properties
| Protein name | Endogenous retrovirus group K member 5 Gag polyprotein |
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| UniProt accession | Q9HDB9 |
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| Gene | ERVK-5 |
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| Organism | Homo sapiens |
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| Length | 667 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9HDB9-F1 | alphafold | PREDICTED | 61.74 | — |
Amino-acid sequence (667 residues)
MGQTKSKTKS KYASYLSFIK ILLKRGGVRV STKNLIKLFQ IIEQFCPWFP EQGTLDLKDW KRIGEELKQA GRKGNIIPLT VWNDWAIIKA ALEPFQTKED SVSVSDAPGS CVIDCNEKTG RKSQKETESL HCEYVTEPVM AQSTQNVDYN QLQGVIYPET LKLEGKGPEL VGPSESKPRG PSPLPAGQVP VTLQPQTQVK ENKTQPPVAY QYWPPAELQY LPPPESQYGY PGMPPALQGR APYPQPPTVR LNPTASRSGQ GGTLHAVIDE ARKQGDLEAW RFLVILQLVQ AGEETQVGAP ARAETRCEPF TMKMLKDIKE GVKQYGSNSP YIRTLLDSIA HGNRLTPYDW ESLAKSSLSS SQYLQFKTWW IDGVQEQVRK NQATKPTVNI DADQLLGTGP NWSTINQQSV MQNEAIEQVR AICLRAWGKI QDPGTAFPIN SIRQGSKEPY PDFVARLQDA AQKSITDDNA RKVIVELMAY ENANPECQSA IKPLKGKVPA GVDVITEYVK ACDGIGGAMH KAMLMAQAMR GLTLGGQVRT FGKKCYNCGQ IGHLKRSCPV LNKQNIINQA ITAKNKKPSG LCPKCGKGKH WANQCHSKFD KDGQPLSGNR KRGQPQAPQQ TGAFPVQLFV PQGFQGQQPL QKIPPLQGVS QLQQSNSCPA PQQAAPQ
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