Phospholipase A and acyltransferase 1 (PLAAT1)

About Phospholipase A and acyltransferase 1

Phospholipase A and acyltransferase 1 (PLAAT1) is a protein from Homo sapiens identified by UniProt accession Q9HDD0, 168 residues long. MolForge cross-references it against 0 known binders and 38 disease associations.

Target properties

Protein name	Phospholipase A and acyltransferase 1
UniProt accession	Q9HDD0
Gene	PLAAT1
Organism	Homo sapiens
Length	168 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (38)

Diseases linked to this target (Open Targets).

Hodgkins lymphoma · score 0.19
daytime rest measurement · score 0.06
Herpes Zoster · score 0.06
Barrett's esophagus · score 0.03
balding measurement · score 0.03
non-small cell lung carcinoma · score 0.03
infect · score 0.02
infection · score 0.02
Abnormal sperm morphology · score 0.02
neoplasm · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9HDD0-F1	alphafold	PREDICTED	71.93	—

Amino-acid sequence (168 residues)

MAFNDCFSLN YPGNPCPGDL IEVFRPGYQH WALYLGDGYV INIAPVDGIP ASFTSAKSVF SSKALVKMQL LKDVVGNDTY RINNKYDETY PPLPVEEIIK RSEFVIGQEV AYNLLVNNCE HFVTLLRYGE GVSEQANRAI STVEFVTAAV GVFSFLGLFP KGQRAKYY

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards