About Zinc finger CCHC domain-containing protein 17
Zinc finger CCHC domain-containing protein 17 (ZCCHC17) is a protein
from Homo sapiens identified by UniProt accession
Q9NP64, 241 residues long.
MolForge cross-references it against 0 known binders and
48 disease associations.
Target properties
| Protein name | Zinc finger CCHC domain-containing protein 17 |
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| UniProt accession | Q9NP64 |
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| Gene | ZCCHC17 |
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| Organism | Homo sapiens |
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| Length | 241 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (48)
Diseases linked to this target (Open Targets).
- cystatin C measurement · score 0.11
- serum urea measurement · score 0.11
- hepatocellular carcinoma · score 0.08
- creatinine measurement · score 0.07
- neoplasm · score 0.06
- hematocrit · score 0.06
- beta-thalassemia-X-linked thrombocytopenia syndrome · score 0.05
- thrombocytopenia 4 · score 0.05
- dominant beta-thalassemia · score 0.04
- macrothrombocytopenia, isolated, 2, autosomal dominant · score 0.04
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9NP64-F1 | alphafold | PREDICTED | 70.80 | — |
Amino-acid sequence (241 residues)
MNSGRPETME NLPALYTIFQ GEVAMVTDYG AFIKIPGCRK QGLVHRTHMS SCRVDKPSEI VDVGDKVWVK LIGREMKNDR IKVSLSMKVV NQGTGKDLDP NNVIIEQEER RRRSFQDYTG QKITLEAVLN TTCKKCGCKG HFAKDCFMQP GGTKYSLIPD EEEEKEEAKS AEFEKPDPTR NPSRKRKKEK KKKKHRDRKS SDSDSSDSES DTGKRARHTS KDSKAAKKKK KKKKHKKKHK E
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