About Palmdelphin
Palmdelphin (PALMD) is a protein
from Homo sapiens identified by UniProt accession
Q9NP74, 551 residues long.
MolForge cross-references it against 0 known binders and
69 disease associations.
Target properties
| Protein name | Palmdelphin |
|---|
| UniProt accession | Q9NP74 |
|---|
| Gene | PALMD |
|---|
| Organism | Homo sapiens |
|---|
| Length | 551 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (69)
Diseases linked to this target (Open Targets).
- serum gamma-glutamyl transferase measurement · score 0.35
- aortic stenosis · score 0.35
- Abnormal heart morphology · score 0.32
- aortic valve calcification · score 0.32
- heel bone mineral density · score 0.31
- heart valve disease · score 0.26
- aortic root size · score 0.26
- congenital anomaly of the great arteries · score 0.26
- Bicuspid aortic valve · score 0.25
- rheumatic heart disease · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9NP74-F1 | alphafold | PREDICTED | 65.69 | — |
Amino-acid sequence (551 residues)
MEEAELVKGR LQAITDKRKI QEEISQKRLK IEEDKLKHQH LKKKALREKW LLDGISSGKE QEEMKKQNQQ DQHQIQVLEQ SILRLEKEIQ DLEKAELQIS TKEEAILKKL KSIERTTEDI IRSVKVEREE RAEESIEDIY ANIPDLPKSY IPSRLRKEIN EEKEDDEQNR KALYAMEIKV EKDLKTGEST VLSSIPLPSD DFKGTGIKVY DDGQKSVYAV SSNHSAAYNG TDGLAPVEVE ELLRQASERN SKSPTEYHEP VYANPFYRPT TPQRETVTPG PNFQERIKIK TNGLGIGVNE SIHNMGNGLS EERGNNFNHI SPIPPVPHPR SVIQQAEEKL HTPQKRLMTP WEESNVMQDK DAPSPKPRLS PRETIFGKSE HQNSSPTCQE DEEDVRYNIV HSLPPDINDT EPVTMIFMGY QQAEDSEEDK KFLTGYDGII HAELVVIDDE EEEDEGEAEK PSYHPIAPHS QVYQPAKPTP LPRKRSEASP HENTNHKSPH KNSISLKEQE ESLGSPVHHS PFDAQTTGDG TEDPSLTALR MRMAKLGKKV I
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