Vacuolar protein sorting-associated protein VTA1…

About Vacuolar protein sorting-associated protein VTA1 homolog

Vacuolar protein sorting-associated protein VTA1 homolog (VTA1) is a protein from Homo sapiens identified by UniProt accession Q9NP79, 307 residues long. MolForge cross-references it against 0 known binders and 37 disease associations.

Target properties

Protein name	Vacuolar protein sorting-associated protein VTA1 homolog
UniProt accession	Q9NP79
Gene	VTA1
Organism	Homo sapiens
Length	307 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (37)

Diseases linked to this target (Open Targets).

HIV infection · score 0.46
forced expiratory volume · score 0.39
vital capacity · score 0.38
FEV/FVC ratio · score 0.33
body height · score 0.30
eye measurement · score 0.27
brain measurement · score 0.26
appendicular lean mass · score 0.23
chronic obstructive pulmonary disease · score 0.22
peak expiratory flow · score 0.21

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9NP79-F1	alphafold	PREDICTED	78.25	—

Amino-acid sequence (307 residues)

MAALAPLPPL PAQFKSIQHH LRTAQEHDKR DPVVAYYCRL YAMQTGMKID SKTPECRKFL SKLMDQLEAL KKQLGDNEAI TQEIVGCAHL ENYALKMFLY ADNEDRAGRF HKNMIKSFYT ASLLIDVITV FGELTDENVK HRKYARWKAT YIHNCLKNGE TPQAGPVGIE EDNDIEENED AGAASLPTQP TQPSSSSTYD PSNMPSGNYT GIQIPPGAHA PANTPAEVPH STGVASNTIQ PTPQTIPAID PALFNTISQG DVRLTPEDFA RAQKYCKYAG SALQYEDVST AVQNLQKALK LLTTGRE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Vacuolar protein sorting-associated protein VTA1 homolog (VTA1)