Sodium- and chloride-dependent transporter XTRP3 (SLC6A20)

Homo sapiens — UniProt Q9NP91

Gene: SLC6A20Homo sapiensSwissProt reviewed

About Sodium- and chloride-dependent transporter XTRP3

Sodium- and chloride-dependent transporter XTRP3 (SLC6A20) is a protein from Homo sapiens identified by UniProt accession Q9NP91, 592 residues long. MolForge cross-references it against 0 known binders and 94 disease associations.

Target properties

Protein nameSodium- and chloride-dependent transporter XTRP3
UniProt accessionQ9NP91
GeneSLC6A20
OrganismHomo sapiens
Length592 residues
Molecular weight—
EC numbers—
Target classUNCLASSIFIED
Subcellular location—
Keywords—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tierMEDIUM
Druggability score—
Pocket score—
Max clinical phase—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

StructureSourceMethodMean pLDDTResolution (Å)
AF-Q9NP91-F1alphafoldPREDICTED93.14—

Amino-acid sequence (592 residues)

MEKARPLWAN SLQFVFACIS YAVGLGNVWR FPYLCQMYGG GSFLVPYIIM LIVEGMPLLY LELAVGQRMR QGSIGAWRTI SPYLSGVGVA SVVVSFFLSM YYNVINAWAF WYLFHSFQDP LPWSVCPLNG NHTGYDEECE KASSTQYFWY RKTLNISPSL QENGGVQWEP ALCLLLAWLV VYLCILRGTE STGKVVYFTA SLPYCVLIIY LIRGLTLHGA TNGLMYMFTP KIEQLANPKA WINAATQIFF SLGLGFGSLI AFASYNEPSN NCQKHAIIVS LINSFTSIFA SIVTFSIYGF KATFNYENCL KKVSLLLTNT FDLEDGFLTA SNLEQVKGYL ASAYPSKYSE MFPQIKNCSL ESELDTAVQG TGLAFIVYTE AIKNMEVSQL WSVLYFFMLL MLGIGSMLGN TAAILTPLTD SKIISSHLPK EAISGLVCLV NCAIGMVFTM EAGNYWFDIF NDYAATLSLL LIVLVETIAV CYVYGLRRFE SDLKAMTGRA VSWYWKVMWA GVSPLLIVSL FVFYLSDYIL TGTLKYQAWD ASQGQLVTKD YPAYALAVIG LLVASSTMCI PLAALGTFVQ RRLKRGDADP VA

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Quick facts

UniProtQ9NP91
GeneSLC6A20
OrganismHomo sapiens
Length592
Binders0
Diseases94
View on UniProt