About Zinc transporter ZIP2
Zinc transporter ZIP2 (SLC39A2) is a protein
from Homo sapiens identified by UniProt accession
Q9NP94, 309 residues long.
MolForge cross-references it against 0 known binders and
32 disease associations.
Target properties
| Protein name | Zinc transporter ZIP2 |
|---|
| UniProt accession | Q9NP94 |
|---|
| Gene | SLC39A2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 309 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (32)
Diseases linked to this target (Open Targets).
- cystic fibrosis · score 0.07
- hemochromatosis type 5 · score 0.03
- FTH1-related iron overload · score 0.03
- GRACILE syndrome · score 0.03
- pulmonary tuberculosis · score 0.03
- Barrett's esophagus · score 0.03
- benign prostatic hyperplasia · score 0.02
- protein measurement · score 0.02
- amino acid measurement · score 0.02
- blood metabolite measurement · score 0.02
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9NP94-F1 | alphafold | PREDICTED | 82.48 | — |
Amino-acid sequence (309 residues)
MEQLLGIKLG CLFALLALTL GCGLTPICFK WFQIDAARGH HRLVLRLLGC ISAGVFLGAG FMHMTAEALE EIESQIQKFM VQNRSASERN SSGDADSAHM EYPYGELIIS LGFFFVFFLE SLALQCCPGA AGGSTVQDEE WGGAHIFELH SHGHLPSPSK GPLRALVLLL SLSFHSVFEG LAVGLQPTVA ATVQLCLAVL AHKGLVVFGV GMRLVHLGTS SRWAVFSILL LALMSPLGLA VGLAVTGGDS EGGRGLAQAV LEGVAAGTFL YVTFLEILPR ELASPEAPLA KWSCVAAGFA FMAFIALWA
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