About Fibroblast growth factor 20
Fibroblast growth factor 20 (FGF20) is a protein
from Homo sapiens identified by UniProt accession
Q9NP95, 211 residues long.
MolForge cross-references it against 0 known binders and
91 disease associations.
Target properties
| Protein name | Fibroblast growth factor 20 |
|---|
| UniProt accession | Q9NP95 |
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| Gene | FGF20 |
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| Organism | Homo sapiens |
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| Length | 211 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (91)
Diseases linked to this target (Open Targets).
- cancer · score 0.60
- bone development disease · score 0.60
- renal agenesis · score 0.40
- Parkinson disease · score 0.38
- craniosynostosis · score 0.37
- bilateral renal agenesis · score 0.37
- acrocephalosyndactyly · score 0.37
- ovarian carcinoma · score 0.37
- female reproductive endometrioid cancer · score 0.37
- thyroid gland adenocarcinoma · score 0.30
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9NP95-F1 | alphafold | PREDICTED | 82.40 | — |
Amino-acid sequence (211 residues)
MAPLAEVGGF LGGLEGLGQQ VGSHFLLPPA GERPPLLGER RSAAERSARG GPGAAQLAHL HGILRRRQLY CRTGFHLQIL PDGSVQGTRQ DHSLFGILEF ISVAVGLVSI RGVDSGLYLG MNDKGELYGS EKLTSECIFR EQFEENWYNT YSSNIYKHGD TGRRYFVALN KDGTPRDGAR SKRHQKFTHF LPRPVDPERV PELYKDLLMY T
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