Dynein light chain roadblock-type 1 (DYNLRB1)

About Dynein light chain roadblock-type 1

Dynein light chain roadblock-type 1 (DYNLRB1) is a protein from Homo sapiens identified by UniProt accession Q9NP97, 96 residues long. MolForge cross-references it against 0 known binders and 106 disease associations.

Target properties

Protein name	Dynein light chain roadblock-type 1
UniProt accession	Q9NP97
Gene	DYNLRB1
Organism	Homo sapiens
Length	96 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (106)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.31
Parkinson disease · score 0.31
multiple sclerosis · score 0.31
lysosomal storage disease · score 0.31
Alzheimer disease · score 0.31
sex hormone-binding globulin measurement · score 0.28
pulse pressure measurement · score 0.12
erythrocyte count · score 0.12
balding measurement · score 0.10
apolipoprotein A 1 measurement · score 0.10

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9NP97-F1	alphafold	PREDICTED	93.17	—

Amino-acid sequence (96 residues)

MAEVEETLKR LQSQKGVQGI IVVNTEGIPI KSTMDNPTTT QYASLMHSFI LKARSTVRDI DPQNDLTFLR IRSKKNEIMV APDKDYFLIV IQNPTE

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards