About Endoplasmic reticulum membrane protein complex subunit 7
Endoplasmic reticulum membrane protein complex subunit 7 (EMC7) is a protein
from Homo sapiens identified by UniProt accession
Q9NPA0, 242 residues long.
MolForge cross-references it against 0 known binders and
15 disease associations.
Target properties
| Protein name | Endoplasmic reticulum membrane protein complex subunit 7 |
|---|
| UniProt accession | Q9NPA0 |
|---|
| Gene | EMC7 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 242 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (15)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.56
- lysosomal storage disease · score 0.37
- genetic disorder · score 0.12
- protein measurement · score 0.04
- infection · score 0.02
- infect · score 0.02
- ovarian carcinoma · score 0.02
- Abnormal sperm morphology · score 0.01
- Plasmodium falciparum malaria · score 0.01
- multiple myeloma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9NPA0-F1 | alphafold | PREDICTED | 72.97 | — |
Amino-acid sequence (242 residues)
MAAALWGFFP VLLLLLLSGD VQSSEVPGAA AEGSGGSGVG IGDRFKIEGR AVVPGVKPQD WISAARVLVD GEEHVGFLKT DGSFVVHDIP SGSYVVEVVS PAYRFDPVRV DITSKGKMRA RYVNYIKTSE VVRLPYPLQM KSSGPPSYFI KRESWGWTDF LMNPMVMMMV LPLLIFVLLP KVVNTSDPDM RREMEQSMNM LNSNHELPDV SEFMTRLFSS KSSGKSSSGS SKTGKSGAGK RR
Explore Endoplasmic reticulum membrane protein complex subunit 7 with MolForge
Find binders, run structure-based screening, and map this target across
diseases and approved drugs with our AI-powered platform.
Browse all targets