About SAYSvFN domain-containing protein 1
SAYSvFN domain-containing protein 1 (SAYSD1) is a protein
from Homo sapiens identified by UniProt accession
Q9NPB0, 183 residues long.
MolForge cross-references it against 0 known binders and
86 disease associations.
Target properties
| Protein name | SAYSvFN domain-containing protein 1 |
|---|
| UniProt accession | Q9NPB0 |
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| Gene | SAYSD1 |
|---|
| Organism | Homo sapiens |
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| Length | 183 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (86)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.26
- urinary albumin to creatinine ratio · score 0.22
- urolithiasis · score 0.22
- myocardial infarction · score 0.17
- diastolic blood pressure · score 0.16
- erythrocyte count · score 0.16
- urate measurement · score 0.14
- coronary artery disease · score 0.14
- hemoglobin measurement · score 0.11
- hematocrit · score 0.10
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9NPB0-F1 | alphafold | PREDICTED | 65.16 | — |
Amino-acid sequence (183 residues)
MEQRLAEFRA ARKRAGLAAQ PPAASQGAQT PGEKAEAAAT LKAAPGWLKR FLVWKPRPAS ARAQPGLVQE AAQPQGSTSE TPWNTAIPLP SCWDQSFLTN ITFLKVLLWL VLLGLFVELE FGLAYFVLSL FYWMYVGTRG PEEKKEGEKS AYSVFNPGCE AIQGTLTAEQ LERELQLRPL AGR
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