E3 ubiquitin-protein ligase CCNB1IP1 (CCNB1IP1)

About E3 ubiquitin-protein ligase CCNB1IP1

E3 ubiquitin-protein ligase CCNB1IP1 (CCNB1IP1) is a protein from Homo sapiens identified by UniProt accession Q9NPC3, 277 residues long. MolForge cross-references it against 0 known binders and 191 disease associations.

Target properties

Protein name	E3 ubiquitin-protein ligase CCNB1IP1
UniProt accession	Q9NPC3
Gene	CCNB1IP1
Organism	Homo sapiens
Length	277 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9NPC3-F1	alphafold	PREDICTED	76.88	—

Amino-acid sequence (277 residues)

MSLCEDMLLC NYRKCRIKLS GYAWVTACSH IFCDQHGSGE FSRSPAICPA CNSTLSGKLD IVRTELSPSE EYKAMVLAGL RPEIVLDISS RALAFWTYQV HQERLYQEYN FSKAEGHLKQ MEKIYTQQIQ SKDVELTSMK GEVTSMKKVL EEYKKKFSDI SEKLMERNRQ YQKLQGLYDS LRLRNITIAN HEGTLEPSMI AQSGVLGFPL GNNSKFPLDN TPVRNRGDGD GDFQFRPFFA GSPTAPEPSN SFFSFVSPSR ELEQQQVSSR AFKVKRI

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards