About Myozenin-2
Myozenin-2 (MYOZ2) is a protein
from Homo sapiens identified by UniProt accession
Q9NPC6, 264 residues long.
MolForge cross-references it against 0 known binders and
213 disease associations.
Target properties
| Protein name | Myozenin-2 |
|---|
| UniProt accession | Q9NPC6 |
|---|
| Gene | MYOZ2 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 264 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (213)
Diseases linked to this target (Open Targets).
- hypertrophic cardiomyopathy · score 0.58
- Rare familial disorder with hypertrophic cardiomyopathy · score 0.44
- PR interval · score 0.33
- sex hormone-binding globulin measurement · score 0.31
- blood urea nitrogen measurement · score 0.25
- high density lipoprotein cholesterol measurement · score 0.20
- Abnormality of the cardiovascular system · score 0.19
- body height · score 0.19
- cardiomyopathy · score 0.19
- familial hypertrophic cardiomyopathy · score 0.15
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9NPC6-F1 | alphafold | PREDICTED | 64.65 | — |
Amino-acid sequence (264 residues)
MLSHNTMMKQ RKQQATAIMK EVHGNDVDGM DLGKKVSIPR DIMLEELSHL SNRGARLFKM RQRRSDKYTF ENFQYQSRAQ INHSIAMQNG KVDGSNLEGG SQQAPLTPPN TPDPRSPPNP DNIAPGYSGP LKEIPPEKFN TTAVPKYYQS PWEQAISNDP ELLEALYPKL FKPEGKAELP DYRSFNRVAT PFGGFEKASR MVKFKVPDFE LLLLTDPRFM SFVNPLSGRR SFNRTPKGWI SENIPIVITT EPTDDTTVPE SEDL
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