Exosome complex component RRP41 (EXOSC4)

About Exosome complex component RRP41

Exosome complex component RRP41 (EXOSC4) is a protein from Homo sapiens identified by UniProt accession Q9NPD3, 245 residues long. MolForge cross-references it against 0 known binders and 39 disease associations.

Target properties

Protein name	Exosome complex component RRP41
UniProt accession	Q9NPD3
Gene	EXOSC4
Organism	Homo sapiens
Length	245 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9NPD3-F1	alphafold	PREDICTED	90.21	—

Amino-acid sequence (245 residues)

MAGLELLSDQ GYRVDGRRAG ELRKIQARMG VFAQADGSAY IEQGNTKALA VVYGPHEIRG SRARALPDRA LVNCQYSSAT FSTGERKRRP HGDRKSCEMG LQLRQTFEAA ILTQLHPRSQ IDIYVQVLQA DGGTYAACVN AATLAVLDAG IPMRDFVCAC SAGFVDGTAL ADLSHVEEAA GGPQLALALL PASGQIALLE MDARLHEDHL ERVLEAAAQA ARDVHTLLDR VVRQHVREAS ILLGD

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards