Neuritin (NRN1)

About Neuritin

Neuritin (NRN1) is a protein from Homo sapiens identified by UniProt accession Q9NPD7, 142 residues long. MolForge cross-references it against 0 known binders and 131 disease associations.

Target properties

Protein name	Neuritin
UniProt accession	Q9NPD7
Gene	NRN1
Organism	Homo sapiens
Length	142 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (131)

Diseases linked to this target (Open Targets).

body mass index · score 0.36
PHF-tau measurement · score 0.32
self reported educational attainment · score 0.26
gut microbiome measurement · score 0.12
protein measurement · score 0.12
melanoma · score 0.09
non-small cell lung carcinoma · score 0.08
neoplasm · score 0.08
renal cell carcinoma · score 0.07
DNA methylation · score 0.07

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9NPD7-F1	alphafold	PREDICTED	78.55	—

Amino-acid sequence (142 residues)

MGLKLNGRYI SLILAVQIAY LVQAVRAAGK CDAVFKGFSD CLLKLGDSMA NYPQGLDDKT NIKTVCTYWE DFHSCTVTAL TDCQEGAKDM WDKLRKESKN LNIQGSLFEL CGSGNGAAGS LLPAFPVLLV SLSAALATWL SF

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards