About Neugrin
Neugrin (NGRN) is a protein
from Homo sapiens identified by UniProt accession
Q9NPE2, 291 residues long.
MolForge cross-references it against 0 known binders and
9 disease associations.
Target properties
| Protein name | Neugrin |
|---|
| UniProt accession | Q9NPE2 |
|---|
| Gene | NGRN |
|---|
| Organism | Homo sapiens |
|---|
| Length | 291 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
|---|
Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (9)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.47
- polyp of colon · score 0.05
- alkaline phosphatase measurement · score 0.04
- metabolite measurement · score 0.03
- cancer · score 0.01
- neuroblastoma · score 0.01
- Cognitive impairment · score 0.00
- Amyotrophic lateral sclerosis · score 0.00
- Lewy body dementia · score 0.00
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9NPE2-F1 | alphafold | PREDICTED | 67.60 | — |
Amino-acid sequence (291 residues)
MAVTLSLLLG GRVCAAVTRC GFATRGVAGP GPIGREPDPD SDWEPEEREL QEVESTLKRQ KQAIRFQKIR RQMEAPGAPP RTLTWEAMEQ IRYLHEEFPE SWSVPRLAEG FDVSTDVIRR VLKSKFLPTL EQKLKQDQKV LKKAGLAHSL QHLRGSGNTS KLLPAGHSVS GSLLMPGHEA SSKDPNHSTA LKVIESDTHR TNTPRRRKGR NKEIQDLEES FVPVAAPLGH PRELQKYSSD SESPRGTGSG ALPSGQKLEE LKAEEPDNFS SKVVQRGREF FDSNGNFLYR I
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