tRNA N6-adenosine threonylcarbamoyltransferase (OSGEP)

About tRNA N6-adenosine threonylcarbamoyltransferase

tRNA N6-adenosine threonylcarbamoyltransferase (OSGEP) is a protein from Homo sapiens identified by UniProt accession Q9NPF4, 335 residues long. MolForge cross-references it against 0 known binders and 44 disease associations.

Target properties

Protein name	tRNA N6-adenosine threonylcarbamoyltransferase
UniProt accession	Q9NPF4
Gene	OSGEP
Organism	Homo sapiens
Length	335 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9NPF4-F1	alphafold	PREDICTED	96.58	—

Amino-acid sequence (335 residues)

MPAVLGFEGS ANKIGVGVVR DGKVLANPRR TYVTPPGTGF LPGDTARHHR AVILDLLQEA LTESGLTSQD IDCIAYTKGP GMGAPLVSVA VVARTVAQLW NKPLVGVNHC IGHIEMGRLI TGATSPTVLY VSGGNTQVIA YSEHRYRIFG ETIDIAVGNC LDRFARVLKI SNDPSPGYNI EQMAKRGKKL VELPYTVKGM DVSFSGILSF IEDVAHRMLA TGECTPEDLC FSLQETVFAM LVEITERAMA HCGSQEALIV GGVGCNVRLQ EMMATMCQER GARLFATDER FCIDNGAMIA QAGWEMFRAG HRTPLSDSGV TQRYRTDEVE VTWRD

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards