Acyl-coenzyme A thioesterase 13 (ACOT13)

About Acyl-coenzyme A thioesterase 13

Acyl-coenzyme A thioesterase 13 (ACOT13) is a protein from Homo sapiens identified by UniProt accession Q9NPJ3, 140 residues long. MolForge cross-references it against 0 known binders and 28 disease associations.

Target properties

Protein name	Acyl-coenzyme A thioesterase 13
UniProt accession	Q9NPJ3
Gene	ACOT13
Organism	Homo sapiens
Length	140 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (28)

Diseases linked to this target (Open Targets).

platelet count · score 0.10
body mass index · score 0.09
testosterone measurement · score 0.08
Autosomal dominant polycystic kidney disease · score 0.05
alkaline phosphatase measurement · score 0.03
body height · score 0.03
osteopathia striata with cranial sclerosis · score 0.02
neoplasm · score 0.02
insulin resistance · score 0.02
Hepatic steatosis · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9NPJ3-F1	alphafold	PREDICTED	96.29	—

Amino-acid sequence (140 residues)

MTSMTQSLRE VIKAMTKARN FERVLGKITL VSAAPGKVIC EMKVEEEHTN AIGTLHGGLT ATLVDNISTM ALLCTERGAP GVSVDMNITY MSPAKLGEDI VITAHVLKQG KTLAFTSVDL TNKATGKLIA QGRHTKHLGN

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards