NTF2-related export protein 2 (NXT2)

About NTF2-related export protein 2

NTF2-related export protein 2 (NXT2) is a protein from Homo sapiens identified by UniProt accession Q9NPJ8, 142 residues long. MolForge cross-references it against 0 known binders and 22 disease associations.

Target properties

Protein name	NTF2-related export protein 2
UniProt accession	Q9NPJ8
Gene	NXT2
Organism	Homo sapiens
Length	142 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (22)

Diseases linked to this target (Open Targets).

gastric carcinoma · score 0.03
gastric ulcer · score 0.03
adolescent idiopathic scoliosis · score 0.02
C-reactive protein measurement · score 0.02
colorectal cancer · score 0.01
bacteriemia · score 0.01
oligodendroglioma · score 0.01
astrocytoma · score 0.01
malaria · score 0.01
Sepsis · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9NPJ8-F1	alphafold	PREDICTED	94.06	—

Amino-acid sequence (142 residues)

MATSLDFKTY VDQACRAAEE FVNIYYETMD KRRRALTRLY LDKATLIWNG NAVSGLDALN NFFDTLPSSE FQVNMLDCQP VHEQATQSQT TVLVVTSGTV KFDGNKQHFF NQNFLLTAQS TPNNTVWKIA SDCFRFQDWS SS

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards