Something about silencing protein 10 (UTP3)

About Something about silencing protein 10

Something about silencing protein 10 (UTP3) is a protein from Homo sapiens identified by UniProt accession Q9NQZ2, 479 residues long. MolForge cross-references it against 0 known binders and 14 disease associations.

Target properties

Protein name	Something about silencing protein 10
UniProt accession	Q9NQZ2
Gene	UTP3
Organism	Homo sapiens
Length	479 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (14)

Diseases linked to this target (Open Targets).

endometrial cancer · score 0.10
diabetes mellitus · score 0.06
heel bone mineral density · score 0.02
mean corpuscular volume · score 0.02
mean corpuscular hemoglobin · score 0.02
mean corpuscular hemoglobin concentration · score 0.02
Red cell distribution width · score 0.02
childhood trauma measurement · score 0.02
alcohol consumption measurement · score 0.02
osteosarcoma · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9NQZ2-F1	alphafold	PREDICTED	68.10	—

Amino-acid sequence (479 residues)

MVGRSRRRGA AKWAAVRAKA GPTLTDENGD DLGLPPSPGD TSYYQDQVDD FHEARSRAAL AKGWNEVQSG DEEDGEEEEE EVLALDMDDE DDEDGGNAGE EEEEENADDD GGSSVQSEAE ASVDPSLSWG QRKKLYYDTD YGSKSRGRQS QQEAEEEERE EEEEAQIIQR RLAQALQEDD FGVAWVEAFA KPVPQVDEAE TRVVKDLAKV SVKEKLKMLR KESPELLELI EDLKVKLTEV KDELEPLLEL VEQGIIPPGK GSQYLRTKYN LYLNYCSNIS FYLILKARRV PAHGHPVIER LVTYRNLINK LSVVDQKLSS EIRHLLTLKD DAVKKELIPK AKSTKPKPKS VSKTSAAACA VTDLSDDSDF DEKAKLKYYK EIEDRQKLKR KKEENSTEEQ ALEDQNAKRA ITYQIAKNRG LTPRRKKIDR NPRVKHREKF RRAKIRRRGQ VREVRKEEQR YSGELSGIRA GVKKSIKLK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards