About Suppressor of tumorigenicity 7 protein
Suppressor of tumorigenicity 7 protein (ST7) is a protein
from Homo sapiens identified by UniProt accession
Q9NRC1, 585 residues long.
MolForge cross-references it against 0 known binders and
33 disease associations.
Target properties
| Protein name | Suppressor of tumorigenicity 7 protein |
|---|
| UniProt accession | Q9NRC1 |
|---|
| Gene | ST7 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 585 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (33)
Diseases linked to this target (Open Targets).
- Seizure · score 0.26
- Brain atrophy · score 0.26
- Global developmental delay · score 0.26
- protein measurement · score 0.22
- platelet count · score 0.11
- mean platelet volume · score 0.11
- erythrocyte count · score 0.10
- platelet component distribution width · score 0.10
- red blood cell density measurement · score 0.09
- platelet crit · score 0.09
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9NRC1-F1 | alphafold | PREDICTED | 80.38 | — |
Amino-acid sequence (585 residues)
MAEAATGFLE QLKSCIVWSW TYLWTVWFFI VLFLVYILRV PLKINDNLST VSMFLNTLTP KFYVALTGTS SLISGLILIF EWWYFRKYGT SFIEQVSVSH LRPLLGGVDN NSSNNSNSSN GDSDSNRQSV SECKVWRNPL NLFRGAEYNR YTWVTGREPL TYYDMNLSAQ DHQTFFTCDS DHLRPADAIM QKAWRERNPQ ARISAAHEAL EINEIRSRVE VPLIASSTIW EIKLLPKCAT AYILLAEEEA TTIAEAEKLF KQALKAGDGC YRRSQQLQHH GSQYEAQHRR DTNVLVYIKR RLAMCARRLG RTREAVKMMR DLMKEFPLLS MFNIHENLLE ALLELQAYAD VQAVLAKYDD ISLPKSATIC YTAALLKARA VSDKFSPEAA SRRGLSTAEM NAVEAIHRAV EFNPHVPKYL LEMKSLILPP EHILKRGDSE AIAYAFFHLA HWKRVEGALN LLHCTWEGTF RMIPYPLEKG HLFYPYPICT ETADRELLPS FHEVSVYPKK ELPFFILFTA GLCSFTAMLA LLTHQFPELM GVFAKAMIDI FCSAEFRDWN CKSIFMRVED ELEIPPAPQS QHFQN
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