Oligosaccharyltransferase complex subunit OSTC (OSTC)

About Oligosaccharyltransferase complex subunit OSTC

Oligosaccharyltransferase complex subunit OSTC (OSTC) is a protein from Homo sapiens identified by UniProt accession Q9NRP0, 149 residues long. MolForge cross-references it against 0 known binders and 21 disease associations.

Target properties

Protein name	Oligosaccharyltransferase complex subunit OSTC
UniProt accession	Q9NRP0
Gene	OSTC
Organism	Homo sapiens
Length	149 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (21)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.46
body height · score 0.20
hair color · score 0.10
hair colour measurement · score 0.09
BMI-adjusted waist circumference · score 0.08
nose morphology measurement · score 0.05
vital capacity · score 0.03
tooth agenesis · score 0.03
FEV/FVC ratio · score 0.02
low density lipoprotein cholesterol measurement · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9NRP0-F1	alphafold	PREDICTED	86.63	—

Amino-acid sequence (149 residues)

METLYRVPFL VLECPNLKLK KPPWLHMPSA MTVYALVVVS YFLITGGIIY DVIVEPPSVG SMTDEHGHQR PVAFLAYRVN GQYIMEGLAS SFLFTMGGLG FIILDRSNAP NIPKLNRFLL LFIGFVCVLL SFFMARVFMR MKLPGYLMG

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards