CDC42 small effector protein 2 (CDC42SE2)

About CDC42 small effector protein 2

CDC42 small effector protein 2 (CDC42SE2) is a protein from Homo sapiens identified by UniProt accession Q9NRR3, 84 residues long. MolForge cross-references it against 0 known binders and 41 disease associations.

Target properties

Protein name	CDC42 small effector protein 2
UniProt accession	Q9NRR3
Gene	CDC42SE2
Organism	Homo sapiens
Length	84 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (41)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.39
eosinophil count · score 0.33
appendicular lean mass · score 0.22
lymphocyte count · score 0.14
mosquito bite reaction itch intensity measurement · score 0.13
mosquito bite reaction size measurement · score 0.11
body mass index · score 0.11
Varicose veins · score 0.11
lean body mass · score 0.11
fat body mass · score 0.11

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9NRR3-F1	alphafold	PREDICTED	67.92	—

Amino-acid sequence (84 residues)

MSEFWLCFNC CIAEQPQPKR RRRIDRSMIG EPTNFVHTAH VGSGDLFSGM NSVSSIQNQM QSKGGYGGGM PANVQMQLVD TKAG

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards