Transmembrane protease serine 4 (TMPRSS4)

About Transmembrane protease serine 4

Transmembrane protease serine 4 (TMPRSS4) is a protein from Homo sapiens identified by UniProt accession Q9NRS4, 437 residues long. MolForge cross-references it against 0 known binders and 110 disease associations.

Target properties

Protein name	Transmembrane protease serine 4
UniProt accession	Q9NRS4
Gene	TMPRSS4
Organism	Homo sapiens
Length	437 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9NRS4-F1	alphafold	PREDICTED	87.87	—

Amino-acid sequence (437 residues)

MLQDPDSDQP LNSLDVKPLR KPRIPMETFR KVGIPIIIAL LSLASIIIVV VLIKVILDKY YFLCGQPLHF IPRKQLCDGE LDCPLGEDEE HCVKSFPEGP AVAVRLSKDR STLQVLDSAT GNWFSACFDN FTEALAETAC RQMGYSSKPT FRAVEIGPDQ DLDVVEITEN SQELRMRNSS GPCLSGSLVS LHCLACGKSL KTPRVVGVEE ASVDSWPWQV SIQYDKQHVC GGSILDPHWV LTAAHCFRKH TDVFNWKVRA GSDKLGSFPS LAVAKIIIIE FNPMYPKDND IALMKLQFPL TFSGTVRPIC LPFFDEELTP ATPLWIIGWG FTKQNGGKMS DILLQASVQV IDSTRCNADD AYQGEVTEKM MCAGIPEGGV DTCQGDSGGP LMYQSDQWHV VGIVSWGYGC GGPSTPGVYT KVSAYLNWIY NVWKAEL

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards