Sorting nexin-15 (SNX15)

About Sorting nexin-15

Sorting nexin-15 (SNX15) is a protein from Homo sapiens identified by UniProt accession Q9NRS6, 342 residues long. MolForge cross-references it against 0 known binders and 24 disease associations.

Target properties

Protein name	Sorting nexin-15
UniProt accession	Q9NRS6
Gene	SNX15
Organism	Homo sapiens
Length	342 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9NRS6-F1	alphafold	PREDICTED	72.38	—

Amino-acid sequence (342 residues)

MSRQAKDDFL RHYTVSDPRT HPKGYTEYKV TAQFISKKDP EDVKEVVVWK RYSDFRKLHG DLAYTHRNLF RRLEEFPAFP RAQVFGRFEA SVIEERRKGA EDLLRFTVHI PALNNSPQLK EFFRGGEVTR PLEVSRDLHI LPPPLIPTPP PDDPRLSQLL PAERRGLEEL EVPVDPPPSS PAQEALDLLF NCESTEEASG SPARGPLTEA ELALFDPFSK EEGAAPSPTH VAELATMEVE SARLDQEPWE PGGQEEEEDG EGGPTPAYLS QATELITQAL RDEKAGAYAA ALQGYRDGVH VLLQGVPSDP LPARQEGVKK KAAEYLKRAE EILRLHLSQL PP

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards