Protein FAM114A2 (FAM114A2)

About Protein FAM114A2

Protein FAM114A2 (FAM114A2) is a protein from Homo sapiens identified by UniProt accession Q9NRY5, 505 residues long. MolForge cross-references it against 0 known binders and 37 disease associations.

Target properties

Protein name	Protein FAM114A2
UniProt accession	Q9NRY5
Gene	FAM114A2
Organism	Homo sapiens
Length	505 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (37)

Diseases linked to this target (Open Targets).

cancer · score 0.54
Red cell distribution width · score 0.41
apolipoprotein A 1 measurement · score 0.34
self reported educational attainment · score 0.28
body mass index · score 0.27
lung adenocarcinoma · score 0.23
sex hormone-binding globulin measurement · score 0.21
breast adenocarcinoma · score 0.18
lean body mass · score 0.16
attempted suicide · score 0.12

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9NRY5-F1	alphafold	PREDICTED	66.08	—

Amino-acid sequence (505 residues)

MSDKDDIETP LLTEAAPILE DGNCEPAKNS ESVDQGAKPE SKSEPVVSTR KRPETKPSSD LETSKVLPIQ DNVSKDVPQT RWGYWGSWGK SILSSASATV ATVGQGISNV IEKAETSLGI PGPSEISTEV KYVAGETNAK ENENSSPVAG AFGVFSTIST AVQSTGKSVI SGGLDALEFI GKKTMDVIAE GDPGFKRTKG LMNRNATLSQ VLREAKEKEE IRTSNEVTVE TDKKTHYGLL FDEFQGLSHL EALEMLSQES EIKVKSILNS LSGEELETLK VELEQLKETF SLAEFCEEEE EEKKGDEDFT KDITELFSQL HVSSKPEKLA RARNTAHEWI RKSLTKPLAE NEEGEKQSEA ENTEQVNKNS IEDIHAFAIR SLAELTACSI ELFHKTAALV LHGRKQEVTA IERSQTLSQM TIVLCKELSS LSKEFTTCLT TAGVKEMADV LNPLITAVFL EASNSASYIQ DAFQLLLPVL EISLIENKIE SHRHELQGQK PLLEH

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards