Sperm protein associated with the nucleus on the X…

About Sperm protein associated with the nucleus on the X chromosome A

Sperm protein associated with the nucleus on the X chromosome A (SPANXA1) is a protein from Homo sapiens identified by UniProt accession Q9NS26, 97 residues long. MolForge cross-references it against 0 known binders and 45 disease associations.

Target properties

Protein name	Sperm protein associated with the nucleus on the X chromosome A
UniProt accession	Q9NS26
Gene	SPANXA1
Organism	Homo sapiens
Length	97 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (45)

Diseases linked to this target (Open Targets).

blood protein measurement · score 0.15
melanoma · score 0.08
neoplasm · score 0.05
cancer · score 0.03
head and neck squamous cell carcinoma · score 0.02
multiple myeloma · score 0.02
glioblastoma multiforme · score 0.01
prostate carcinoma · score 0.01
cutaneous melanoma · score 0.01
Infertility · score 0.01

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9NS26-F1	alphafold	PREDICTED	65.63	—

Amino-acid sequence (97 residues)

MDKQSSAGGV KRSVPCDSNE ANEMMPETPT GDSDPQPAPK KMKTSESSTI LVVRYRRNFK RTSPEELLND HARENRINPL QMEEEEFMEI MVEIPAK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards

Sperm protein associated with the nucleus on the X chromosome A (SPANXA1)