Protein reprimo (RPRM)

About Protein reprimo

Protein reprimo (RPRM) is a protein from Homo sapiens identified by UniProt accession Q9NS64, 109 residues long. MolForge cross-references it against 0 known binders and 32 disease associations.

Target properties

Protein name	Protein reprimo
UniProt accession	Q9NS64
Gene	RPRM
Organism	Homo sapiens
Length	109 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (32)

Diseases linked to this target (Open Targets).

mathematical ability · score 0.26
metabolite measurement · score 0.12
osteoarthritis · score 0.10
gut microbiome measurement · score 0.10
PHF-tau measurement · score 0.07
renal cell carcinoma · score 0.04
lung carcinoma · score 0.02
gonorrhea · score 0.02
neoplasm · score 0.02
insulin resistance · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9NS64-F1	alphafold	PREDICTED	60.84	—

Amino-acid sequence (109 residues)

MNPALGNQTD VAGLFLANSS EALERAVRCC TQASVVTDDG FAEGGPDERS LYIMRVVQIA VMCVLSLTVV FGIFFLGCNL LIKSEGMINF LVKDRRPSKE VEAVVVGPY

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards