Asc-type amino acid transporter 1 (SLC7A10)

About Asc-type amino acid transporter 1

Asc-type amino acid transporter 1 (SLC7A10) is a protein from Homo sapiens identified by UniProt accession Q9NS82, 523 residues long. MolForge cross-references it against 0 known binders and 141 disease associations.

Target properties

Protein name	Asc-type amino acid transporter 1
UniProt accession	Q9NS82
Gene	SLC7A10
Organism	Homo sapiens
Length	523 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (141)

Diseases linked to this target (Open Targets).

mean corpuscular volume · score 0.35
erythrocyte count · score 0.34
basophil count · score 0.34
eosinophil count · score 0.34
mean corpuscular hemoglobin · score 0.33
basophil percentage of leukocytes · score 0.32
monocyte count · score 0.31
allergic rhinitis · score 0.31
platelet count · score 0.31
mean corpuscular hemoglobin concentration · score 0.31

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9NS82-F1	alphafold	PREDICTED	83.40	—

Amino-acid sequence (523 residues)

MAGHTQQPSG RGNPRPAPSP SPVPGTVPGA SERVALKKEI GLLSACTIII GNIIGSGIFI SPKGVLEHSG SVGLALFVWV LGGGVTALGS LCYAELGVAI PKSGGDYAYV TEIFGGLAGF LLLWSAVLIM YPTSLAVISM TFSNYVLQPV FPNCIPPTTA SRVLSMACLM LLTWVNSSSV RWATRIQDMF TGGKLLALSL IIGVGLLQIF QGHFEELRPS NAFAFWMTPS VGHLALAFLQ GSFAFSGWNF LNYVTEEMVD ARKNLPRAIF ISIPLVTFVY TFTNIAYFTA MSPQELLSSN AVAVTFGEKL LGYFSWVMPV SVALSTFGGI NGYLFTYSRL CFSGAREGHL PSLLAMIHVR HCTPIPALLV CCGATAVIML VGDTYTLINY VSFINYLCYG VTILGLLLLR WRRPALHRPI KVNLLIPVAY LVFWAFLLVF SFISEPMVCG VGVIIILTGV PIFFLGVFWR SKPKCVHRLT ESMTHWGQEL CFVVYPQDAP EEEENGPCPP SLLPATDKPS KPQ

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards