About Carbohydrate sulfotransferase 7
Carbohydrate sulfotransferase 7 (CHST7) is a protein
from Homo sapiens identified by UniProt accession
Q9NS84, 486 residues long.
MolForge cross-references it against 0 known binders and
30 disease associations.
Target properties
| Protein name | Carbohydrate sulfotransferase 7 |
|---|
| UniProt accession | Q9NS84 |
|---|
| Gene | CHST7 |
|---|
| Organism | Homo sapiens |
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| Length | 486 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (30)
Diseases linked to this target (Open Targets).
- neurodegenerative disease · score 0.37
- mental or behavioural disorder · score 0.18
- Sepsis · score 0.02
- gonorrhea · score 0.02
- systemic scleroderma · score 0.02
- esophageal squamous cell carcinoma · score 0.01
- Tetralogy of Fallot · score 0.01
- neoplasm · score 0.01
- cancer · score 0.01
- Pituitary Gland Adenoma · score 0.01
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9NS84-F1 | alphafold | PREDICTED | 79.26 | — |
Amino-acid sequence (486 residues)
MKGRRRRRRE YCKFALLLVL YTLVLLLVPS VLDGGRDGDK GAEHCPGLQR SLGVWSLEAA AAGEREQGAE ARAAEEGGAN QSPRFPSNLS GAVGEAVSRE KQHIYVHATW RTGSSFLGEL FNQHPDVFYL YEPMWHLWQA LYPGDAESLQ GALRDMLRSL FRCDFSVLRL YAPPGDPAAR APDTANLTTA ALFRWRTNKV ICSPPLCPGA PRARAEVGLV EDTACERSCP PVAIRALEAE CRKYPVVVIK DVRLLDLGVL VPLLRDPGLN LKVVQLFRDP RAVHNSRLKS RQGLLRESIQ VLRTRQRGDR FHRVLLAHGV GARPGGQSRA LPAAPRADFF LTGALEVICE AWLRDLLFAR GAPAWLRRRY LRLRYEDLVR QPRAQLRRLL RFSGLRALAA LDAFALNMTR GAAYGADRPF HLSARDAREA VHAWRERLSR EQVRQVEAAC APAMRLLAYP RSGEEGDAEQ PREGETPLEM DADGAT
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