Carbonic anhydrase-related protein 10 (CA10)

About Carbonic anhydrase-related protein 10

Carbonic anhydrase-related protein 10 (CA10) is a protein from Homo sapiens identified by UniProt accession Q9NS85, 328 residues long. MolForge cross-references it against 0 known binders and 73 disease associations.

Target properties

Protein name	Carbonic anhydrase-related protein 10
UniProt accession	Q9NS85
Gene	CA10
Organism	Homo sapiens
Length	328 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (73)

Diseases linked to this target (Open Targets).

smoking status measurement · score 0.46
blood protein measurement · score 0.43
smoking behavior · score 0.43
chronotype measurement · score 0.43
gastroesophageal reflux disease · score 0.41
multisite chronic pain · score 0.40
self reported educational attainment · score 0.39
mathematical ability · score 0.38
insomnia measurement · score 0.37
smoking initiation · score 0.36

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9NS85-F1	alphafold	PREDICTED	85.79	—

Amino-acid sequence (328 residues)

MEIVWEVLFL LQANFIVCIS AQQNSPKIHE GWWAYKEVVQ GSFVPVPSFW GLVNSAWNLC SVGKRQSPVN IETSHMIFDP FLTPLRINTG GRKVSGTMYN TGRHVSLRLD KEHLVNISGG PMTYSHRLEE IRLHFGSEDS QGSEHLLNGQ AFSGEVQLIH YNHELYTNVT EAAKSPNGLV VVSIFIKVSD SSNPFLNRML NRDTITRITY KNDAYLLQGL NIEELYPETS SFITYDGSMT IPPCYETASW IIMNKPVYIT RMQMHSLRLL SQNQPSQIFL SMSDNFRPVQ PLNNRCIRTN INFSLQGKDC PNNRAQKLQY RVNEWLLK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards