About Solute carrier family 22 member 11
Solute carrier family 22 member 11 (SLC22A11) is a protein
from Homo sapiens identified by UniProt accession
Q9NSA0, 550 residues long.
MolForge cross-references it against 0 known binders and
57 disease associations.
Target properties
| Protein name | Solute carrier family 22 member 11 |
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| UniProt accession | Q9NSA0 |
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| Gene | SLC22A11 |
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| Organism | Homo sapiens |
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| Length | 550 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
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| Max clinical phase | — |
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Approved drugs hitting this target (3)
DrugCentral-linked approved drugs that act on this protein.
Disease associations (57)
Diseases linked to this target (Open Targets).
- urate measurement · score 0.62
- gout · score 0.60
- testosterone measurement · score 0.43
- influenza · score 0.37
- epilepsy · score 0.37
- urinary tract infection · score 0.35
- neurodegenerative disease · score 0.32
- infection · score 0.27
- obesity · score 0.27
- uric acid measurement · score 0.27
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9NSA0-F1 | alphafold | PREDICTED | 87.60 | — |
Amino-acid sequence (550 residues)
MAFSKLLEQA GGVGLFQTLQ VLTFILPCLM IPSQMLLENF SAAIPGHRCW THMLDNGSAV STNMTPKALL TISIPPGPNQ GPHQCRRFRQ PQWQLLDPNA TATSWSEADT EPCVDGWVYD RSVFTSTIVA KWDLVCSSQG LKPLSQSIFM SGILVGSFIW GLLSYRFGRK PMLSWCCLQL AVAGTSTIFA PTFVIYCGLR FVAAFGMAGI FLSSLTLMVE WTTTSRRAVT MTVVGCAFSA GQAALGGLAF ALRDWRTLQL AASVPFFAIS LISWWLPESA RWLIIKGKPD QALQELRKVA RINGHKEAKN LTIEVLMSSV KEEVASAKEP RSVLDLFCVP VLRWRSCAML VVNFSLLISY YGLVFDLQSL GRDIFLLQAL FGAVDFLGRA TTALLLSFLG RRTIQAGSQA MAGLAILANM LVPQDLQTLR VVFAVLGKGC FGISLTCLTI YKAELFPTPV RMTADGILHT VGRLGAMMGP LILMSRQALP LLPPLLYGVI SIASSLVVLF FLPETQGLPL PDTIQDLESQ KSTAAQGNRQ EAVTVESTSL
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