Beta-catenin-interacting protein 1 (CTNNBIP1)

About Beta-catenin-interacting protein 1

Beta-catenin-interacting protein 1 (CTNNBIP1) is a protein from Homo sapiens identified by UniProt accession Q9NSA3, 81 residues long. MolForge cross-references it against 0 known binders and 101 disease associations.

Target properties

Protein name	Beta-catenin-interacting protein 1
UniProt accession	Q9NSA3
Gene	CTNNBIP1
Organism	Homo sapiens
Length	81 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (101)

Diseases linked to this target (Open Targets).

platelet component distribution width · score 0.36
hematocrit · score 0.08
hepatocellular carcinoma · score 0.08
erythrocyte count · score 0.07
adolescent idiopathic scoliosis · score 0.07
papillary thyroid carcinoma · score 0.06
essential thrombocythemia · score 0.05
acute myeloid leukemia · score 0.05
thrombocythemia 2 · score 0.05
beta-thalassemia-X-linked thrombocytopenia syndrome · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9NSA3-F1	alphafold	PREDICTED	79.00	—

Amino-acid sequence (81 residues)

MNREGAPGKS PEEMYIQQKV RVLLMLRKMG SNLTASEEEF LRTYAGVVNS QLSQLPPHSI DQGAEDVVMA FSRSETEDRR Q

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards