About Protein C19orf12
Protein C19orf12 (C19orf12) is a protein
from Homo sapiens identified by UniProt accession
Q9NSK7, 141 residues long.
MolForge cross-references it against 0 known binders and
80 disease associations.
Target properties
| Protein name | Protein C19orf12 |
|---|
| UniProt accession | Q9NSK7 |
|---|
| Gene | C19orf12 |
|---|
| Organism | Homo sapiens |
|---|
| Length | 141 residues |
|---|
| Molecular weight | — |
|---|
| EC numbers | — |
|---|
| Target class | UNCLASSIFIED |
|---|
| Subcellular location | — |
|---|
| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (80)
Diseases linked to this target (Open Targets).
- neurodegeneration with brain iron accumulation 4 · score 0.85
- hereditary spastic paraplegia 43 · score 0.69
- Autosomal recessive spastic paraplegia type 43 · score 0.69
- neurodegeneration with brain iron accumulation · score 0.51
- hereditary spastic paraplegia · score 0.46
- Mental deterioration · score 0.34
- Dystonia · score 0.34
- dystonic disorder · score 0.34
- Tremor · score 0.34
- essential tremor · score 0.34
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9NSK7-F1 | alphafold | PREDICTED | 60.06 | — |
Amino-acid sequence (141 residues)
MTIMVEDIMK LLCSLSGERK MKAAVKHSGK GALVTGAMAF VGGLVGGPPG LAVGGAVGGL LGAWMTSGQF KPVPQILMEL PPAEQQRLFN EAAAIIRHLE WTDAVQLTAL VMGSEALQQQ LLAMLVNYVT KELRAEIQYD D
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