Zinc transporter ZIP9 (SLC39A9)

About Zinc transporter ZIP9

Zinc transporter ZIP9 (SLC39A9) is a protein from Homo sapiens identified by UniProt accession Q9NUM3, 307 residues long. MolForge cross-references it against 0 known binders and 47 disease associations.

Target properties

Protein name	Zinc transporter ZIP9
UniProt accession	Q9NUM3
Gene	SLC39A9
Organism	Homo sapiens
Length	307 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (47)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.46
neutrophil count · score 0.46
leukocyte count · score 0.42
neutrophil percentage of leukocytes · score 0.39
myeloid white cell count · score 0.35
lymphocyte percentage of leukocytes · score 0.35
granulocyte percentage of myeloid white cells · score 0.29
sum of basophil and neutrophil counts · score 0.28
sum of neutrophil and eosinophil counts · score 0.28
IGF-1 measurement · score 0.28

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9NUM3-F1	alphafold	PREDICTED	79.72	—

Amino-acid sequence (307 residues)

MDDFISISLL SLAMLVGCYV AGIIPLAVNF SEERLKLVTV LGAGLLCGTA LAVIVPEGVH ALYEDILEGK HHQASETHNV IASDKAAEKS VVHEHEHSHD HTQLHAYIGV SLVLGFVFML LVDQIGNSHV HSTDDPEAAR SSNSKITTTL GLVVHAAADG VALGAAASTS QTSVQLIVFV AIMLHKAPAA FGLVSFLMHA GLERNRIRKH LLVFALAAPV MSMVTYLGLS KSSKEALSEV NATGVAMLFS AGTFLYVATV HVLPEVGGIG HSHKPDATGG RGLSRLEVAA LVLGCLIPLI LSVGHQH

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards