Protein lin-7 homolog C (LIN7C)

About Protein lin-7 homolog C

Protein lin-7 homolog C (LIN7C) is a protein from Homo sapiens identified by UniProt accession Q9NUP9, 197 residues long. MolForge cross-references it against 0 known binders and 184 disease associations.

Target properties

Protein name	Protein lin-7 homolog C
UniProt accession	Q9NUP9
Gene	LIN7C
Organism	Homo sapiens
Length	197 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (184)

Diseases linked to this target (Open Targets).

bone density · score 0.32
body mass index · score 0.25
neurodegenerative disease · score 0.22
lean body mass · score 0.20
heel bone mineral density · score 0.17
brain measurement · score 0.13
neuroimaging measurement · score 0.13
bone disease · score 0.12
body fat percentage · score 0.12
fat body mass · score 0.10

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9NUP9-F1	alphafold	PREDICTED	87.36	—

Amino-acid sequence (197 residues)

MAALGEPVRL ERDICRAIEL LEKLQRSGEV PPQKLQALQR VLQSEFCNAV REVYEHVYET VDISSSPEVR ANATAKATVA AFAASEGHSH PRVVELPKTE EGLGFNIMGG KEQNSPIYIS RIIPGGIADR HGGLKRGDQL LSVNGVSVEG EHHEKAVELL KAAQGKVKLV VRYTPKVLEE MESRFEKMRS AKRRQQT

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards