DDB1- and CUL4-associated factor 13 (DCAF13)

About DDB1- and CUL4-associated factor 13

DDB1- and CUL4-associated factor 13 (DCAF13) is a protein from Homo sapiens identified by UniProt accession Q9NV06, 445 residues long. MolForge cross-references it against 0 known binders and 23 disease associations.

Target properties

Protein name	DDB1- and CUL4-associated factor 13
UniProt accession	Q9NV06
Gene	DCAF13
Organism	Homo sapiens
Length	445 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (23)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.29
erythrocyte count · score 0.20
lung adenocarcinoma · score 0.08
red blood cell density measurement · score 0.06
neoplasm · score 0.05
Mantle cell lymphoma · score 0.03
cancer · score 0.03
triple-negative breast cancer · score 0.03
hepatocellular carcinoma · score 0.03
head and neck squamous cell carcinoma · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9NV06-F1	alphafold	PREDICTED	92.77	—

Amino-acid sequence (445 residues)

MKVKMLSRNP DNYVRETKLD LQRVPRNYDP ALHPFEVPRE YIRALNATKL ERVFAKPFLA SLDGHRDGVN CLAKHPEKLA TVLSGACDGE VRIWNLTQRN CIRTIQAHEG FVRGICTRFC GTSFFTVGDD KTVKQWKMDG PGYGDEEEPL HTILGKTVYT GIDHHWKEAV FATCGQQVDI WDEQRTNPIC SMTWGFDSIS SVKFNPIETF LLGSCASDRN IVLYDMRQAT PLKKVILDMR TNTICWNPME AFIFTAANED YNLYTFDMRA LDTPVMVHMD HVSAVLDVDY SPTGKEFVSA SFDKSIRIFP VDKSRSREVY HTKRMQHVIC VKWTSDSKYI MCGSDEMNIR LWKANASEKL GVLTSREKAA KDYNQKLKEK FQHYPHIKRI ARHRHLPKSI YSQIQEQRIM KEARRRKEVN RIKHSKPGSV PLVSEKKKHV VAVVK

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards