Cell cycle control protein 50A (TMEM30A)

About Cell cycle control protein 50A

Cell cycle control protein 50A (TMEM30A) is a protein from Homo sapiens identified by UniProt accession Q9NV96, 361 residues long. MolForge cross-references it against 0 known binders and 77 disease associations.

Target properties

Protein name	Cell cycle control protein 50A
UniProt accession	Q9NV96
Gene	TMEM30A
Organism	Homo sapiens
Length	361 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (77)

Diseases linked to this target (Open Targets).

neurodegenerative disease · score 0.41
cortical thickness · score 0.10
neoplasm · score 0.09
cortical surface area measurement · score 0.07
vital capacity · score 0.06
cancer · score 0.03
ovarian neoplasm · score 0.02
protein measurement · score 0.02
hepatocellular carcinoma · score 0.02
Obesity · score 0.02

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9NV96-F1	alphafold	PREDICTED	89.49	—

Amino-acid sequence (361 residues)

MAMNYNAKDE VDGGPPCAPG GTAKTRRPDN TAFKQQRLPA WQPILTAGTV LPIFFIIGLI FIPIGIGIFV TSNNIREIEI DYTGTEPSSP CNKCLSPDVT PCFCTINFTL EKSFEGNVFM YYGLSNFYQN HRRYVKSRDD SQLNGDSSAL LNPSKECEPY RRNEDKPIAP CGAIANSMFN DTLELFLIGN DSYPIPIALK KKGIAWWTDK NVKFRNPPGG DNLEERFKGT TKPVNWLKPV YMLDSDPDNN GFINEDFIVW MRTAALPTFR KLYRLIERKS DLHPTLPAGR YSLNVTYNYP VHYFDGRKRM ILSTISWMGG KNPFLGIAYI AVGSISFLLG VVLLVINHKY RNSSNTADIT I

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards