About Sodium-coupled neutral amino acid transporter 7
Sodium-coupled neutral amino acid transporter 7 (SLC38A7) is a protein
from Homo sapiens identified by UniProt accession
Q9NVC3, 462 residues long.
MolForge cross-references it against 0 known binders and
195 disease associations.
Target properties
| Protein name | Sodium-coupled neutral amino acid transporter 7 |
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| UniProt accession | Q9NVC3 |
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| Gene | SLC38A7 |
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| Organism | Homo sapiens |
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| Length | 462 residues |
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| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
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| Druggability score | — |
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| Pocket score | — |
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| Max clinical phase | — |
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Disease associations (195)
Diseases linked to this target (Open Targets).
- response to aromatase inhibitor · score 0.40
- neuroimaging measurement · score 0.23
- brain volume measurement · score 0.18
- brain measurement · score 0.18
- malignant epithelial tumor of ovary · score 0.08
- urate measurement · score 0.08
- bone density · score 0.08
- self reported educational attainment · score 0.07
- blood metabolite measurement · score 0.07
- aspartate aminotransferase measurement · score 0.06
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9NVC3-F1 | alphafold | PREDICTED | 84.30 | — |
Amino-acid sequence (462 residues)
MAQVSINNDY SEWDLSTDAG ERARLLQSPC VDTAPKSEWE ASPGGLDRGT TSTLGAIFIV VNACLGAGLL NFPAAFSTAG GVAAGIALQM GMLVFIISGL VILAYCSQAS NERTYQEVVW AVCGKLTGVL CEVAIAVYTF GTCIAFLIII GDQQDKIIAV MAKEPEGASG PWYTDRKFTI SLTAFLFILP LSIPREIGFQ KYASFLSVVG TWYVTAIVII KYIWPDKEMT PGNILTRPAS WMAVFNAMPT ICFGFQCHVS SVPVFNSMQQ PEVKTWGGVV TAAMVIALAV YMGTGICGFL TFGAAVDPDV LLSYPSEDMA VAVARAFIIL SVLTSYPILH FCGRAVVEGL WLRYQGVPVE EDVGRERRRR VLQTLVWFLL TLLLALFIPD IGKVISVIGG LAACFIFVFP GLCLIQAKLS EMEEVKPASW WVLVSYGVLL VTLGAFIFGQ TTANAIFVDL LA
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