Histone chaperone ASF1B (ASF1B)

About Histone chaperone ASF1B

Histone chaperone ASF1B (ASF1B) is a protein from Homo sapiens identified by UniProt accession Q9NVP2, 202 residues long. MolForge cross-references it against 0 known binders and 96 disease associations.

Target properties

Protein name	Histone chaperone ASF1B
UniProt accession	Q9NVP2
Gene	ASF1B
Organism	Homo sapiens
Length	202 residues
Molecular weight	—
EC numbers	—
Target class	UNCLASSIFIED
Subcellular location	—
Keywords	—

Druggability

Target tractability assessment (Open Targets + pocket analysis). No approved drug

Druggability tier	MEDIUM
Druggability score	—
Pocket score	—
Max clinical phase	—

Disease associations (96)

Diseases linked to this target (Open Targets).

body height · score 0.13
neoplasm · score 0.11
cancer · score 0.11
hepatocellular carcinoma · score 0.11
lung adenocarcinoma · score 0.10
gonorrhea · score 0.09
melanoma · score 0.08
gastric adenocarcinoma · score 0.08
metabolite measurement · score 0.05
immune deficiency, familial variable · score 0.05

3D Structure (1)

Experimental (PDB) and predicted (AlphaFold) structures for this protein.

Structure	Source	Method	Mean pLDDT	Resolution (Å)
AF-Q9NVP2-F1	alphafold	PREDICTED	84.57	—

Amino-acid sequence (202 residues)

MAKVSVLNVA VLENPSPFHS PFRFEISFEC SEALADDLEW KIIYVGSAES EEFDQILDSV LVGPVPAGRH MFVFQADAPN PSLIPETDAV GVTVVLITCT YHGQEFIRVG YYVNNEYLNP ELRENPPMKP DFSQLQRNIL ASNPRVTRFH INWDNNMDRL EAIETQDPSL GCGLPLNCTP IKGLGLPGCI PGLLPENSMD CI

External references

UniProt AlphaFold QuickGO RCSB PDB GeneCards