About TBCC domain-containing protein 1
TBCC domain-containing protein 1 (TBCCD1) is a protein
from Homo sapiens identified by UniProt accession
Q9NVR7, 557 residues long.
MolForge cross-references it against 0 known binders and
83 disease associations.
Target properties
| Protein name | TBCC domain-containing protein 1 |
|---|
| UniProt accession | Q9NVR7 |
|---|
| Gene | TBCCD1 |
|---|
| Organism | Homo sapiens |
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| Length | 557 residues |
|---|
| Molecular weight | — |
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| EC numbers | — |
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| Target class | UNCLASSIFIED |
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| Subcellular location | — |
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| Keywords | — |
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Druggability
Target tractability assessment (Open Targets + pocket analysis). No approved drug
| Druggability tier | MEDIUM |
|---|
| Druggability score | — |
|---|
| Pocket score | — |
|---|
| Max clinical phase | — |
|---|
Disease associations (83)
Diseases linked to this target (Open Targets).
- calcium measurement · score 0.23
- gut microbiome measurement · score 0.20
- blood protein measurement · score 0.20
- systolic blood pressure · score 0.16
- leukocyte count · score 0.16
- open-angle glaucoma · score 0.14
- PHF-tau measurement · score 0.14
- cup-to-disc ratio measurement · score 0.12
- neutrophil count · score 0.12
- illegal drug consumption · score 0.07
3D Structure (1)
Experimental (PDB) and predicted (AlphaFold) structures for this protein.
| Structure | Source | Method | Mean pLDDT | Resolution (Å) |
|---|
| AF-Q9NVR7-F1 | alphafold | PREDICTED | 86.59 | — |
Amino-acid sequence (557 residues)
MDQSRVLLWV KAEPFIVGAL QVPPPSKFSL HYLRKISTYV QIRATEGAYP RLYWSTWRHI ACGKLQLAKD LAWLYFEIFD SLSMKTPEER LEWSEVLSNC MSEEEVEKQR NQLSVDTLQF LLFLYIQQLN KVSLRTSLIG EEWPSPRNKS QSPDLTEKSN CHNKNWNDYS HQAFVYDHLS DLLELLLDPK QLTASFHSTH SSLVSREAVV ALSFLIEGTI SRARKIYPLH ELALWQPLHA DSGFSKISKT FSFYKLETWL RSCLTGNPFG TSACLKSGKK LAWAHQVEGT TKRAKIACNT HVAPRMHRLV VMSQVYKQTL AKSSDTLAGA HVKIHRCNES FIYLLSPLRS VTIEKCRNSI FVLGPVGTTL HLHSCDNVKV IAVCHRLSIS STTGCIFHVL TPTRPLILSG NQTVTFAPFH THYPMLEDHM ARTGLATVPN YWDNPMVVCR ENSDTRVFQL LPPCEFYVFI IPFEMEGDTT EIPGGLPSVY QKALGQREQK IQIWQKTVKE AHLTKDQRKQ FQVLVENKFY EWLINTGHRQ QLDSLVPPAA GSKQAAG
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